Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
You can also use a * character as a wildcard at the start of a alphanumeric search term. However you must use forward slashes to delimit the search term and use a point before the wildcard. E.g., /.*picin/ will only get you “Rifampicin”.

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Found 149 Matches

Creatinine_MechKiM_V16R1_UniversityOfManchester_20210421

Model Files Publication

https://doi.org/10.1124/jpet.118.251413 Creatinine compound file with MechKiM

Search Score: 1

Ertugliflozin_V15R1_Pfizer_20220726

Model Files Publication

Ertugliflozin compound file, UGT1A9 and UGT2B4/7 substrate. Model developed and verified using ADME, IV PK and SD/MD clinical data. Simulated DDI with UGT inhibitor mefenamic acid. https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/psp4.12581

Search Score: 1

Ondansetron_V14R1_AstraZeneca_20200427

Model Files Publication

Ondansetron adult compound file for paediatric prediction.

Search Score: 1

Paclitaxel_RES_V17R1_Simcyp_20180228

Model Files Publication

Simcyp developed Paclitaxel compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Search Score: 1

Search the PBPK Model Repository

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Creatinine_MechKiM_V16R1_UniversityOfManchester_20210421

Ertugliflozin_V15R1_Pfizer_20220726

Ondansetron_V14R1_AstraZeneca_20200427

Paclitaxel_RES_V17R1_Simcyp_20180228

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