Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 70 Matches

Nicotine_MechKiM_V16R1_UniversityOfManchester_20210421
https://doi.org/10.1124/jpet.118.251413 Nicotine compound file with MechKiM
Non_Alcoholic_Steatohepatitis_Population_RES_V22R1_Simcyp_20231114

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Fluoxetine&Norfluoxetine_V12R2_USFDA_20160511
Optimized, personal communication with Dr. Snoeys
EsomeprazoleCapsule_V14R1_AstraZeneca_20200427
https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/cpt.905 Esomeprazole adult compound file for pediatric prediction. The following parameters need to be updated, as compared to Table 2 in the manuscript: Ka=1.331/h, tlag=1h, fu,gut=0.048

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