Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 112 Matches

Aripiprazole_V12R2_USFDA_20160510
Note: additional dissolution data 0.5 hr 55% not captured in the supplemental materials of the publication
Osimertinib_V14R1_AstraZeneca_20190717
Compound file from publication: Development, Verification, and Prediction of Osimertinib Drug-Drug Interactions Using PBPK Modeling Approach to Inform Drug Label. Pilla Reddy V, Walker M, Sharma P, Ballard P, Vishwanathan K (2018). CPT Pharmacometrics Systems Pharmacolology. doi: 10.1002/psp4.12289.
Ganciclovir_V15R1_USFDA_20170810
http://onlinelibrary.wiley.com/doi/10.1002/cpt.750/full Ganciclovir compound file in healthy volunteers. Evaluation of the effect of renal impairment on the PK of OAT substrates. NOTE: Kp scaler in model should be 0.33, different from Table 1.
Acyclovir_MechKiM_V16R1_UniversityOfManchester_20210421
https://doi.org/10.1124/jpet.118.251413 Acyclovir compound file with MechKiM. The Acyclovir file was verified with IV data.

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