Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 108 Matches

Tizanidine_RES_V18R1_Simcyp_20190809

Simcyp developed tizanidine compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Creatinine_MechKiM_V16R1_UniversityOfManchester_20210421
https://doi.org/10.1124/jpet.118.251413 Creatinine compound file with MechKiM
Sulfamethoxazole_MechKiM_V16R1_UniversityOfManchester_20210421
https://doi.org/10.1124/jpet.118.251413 Sulfamethoxazole compound file with MechKiM
Hydroxychloroquine_V18R1_PekingUniversityThirdHospital_20220209
PBPK model of Hydroxychloroquine and its metabolite of Desethyl-hydroxychloroquine. This file is a further development of the file for Hydroxychloroquine (V18R1) also available within this database: In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) - PubMed (nih.gov)

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