Quickly find freely available drug and population models in our PBPK model repository.
The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.>
You can use a suffix operator (*) as the placeholder for end of a term. The query must start with at least one alphanumeric character before the suffix operator. E.g., Rifam* will get you “Rifampicin” and “Rifampin”. For more advanced searching tips click here.
Brand Name(s) include: Camoquin (FDC with amodiaquine)
Disease: Malaria
Drug Class: Antimalarials
Related Drugs: DHA, Amodiaquine
Date Updated: March 2022
Absorption Model |
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Volume of Distribution |
Note: Kp scalar used |
Route of Elimination |
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Perpetrator DDI |
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Validation |
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Limitations |
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Updates in V19 |
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Brand Name(s) include: Lariam, Mephaquin, Mefliam
Disease: Malaria
Drug Class: Antimalarials
Date Updated: November 2021
Absorption Model |
First-Order |
Volume of Distribution |
Full PBPK (Method 2) |
Route of Elimination |
CYP3A4 (fm =100); renal clearance (fe = 0.05) |
Perpetrator DDI |
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Validation |
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Limitations |
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Updates in V19 |
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4 |