Quickly find freely available drug and population models in our PBPK model repository.
The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.>
You can use a suffix operator (*) as the placeholder for end of a term. The query must start with at least one alphanumeric character before the suffix operator. E.g., Rifam* will get you “Rifampicin” and “Rifampin”. For more advanced searching tips click here.
Brand Name(s) include: Biltricide, Cysticide, Praquantel
Indication: Schistosomiasis and clonorchiasis/opisthorchiasis due to the liver flukes
Drug Class: Anthelmintic
Version: 22
Date Updated: February 2024
Absorption Model |
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Volume of Distribution Details |
Full model (method 3) |
Route of Elimination |
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Perpetrator DDI |
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Validation |
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Limitations |
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Brand Name(s) include: Basoquin, Camoquin, Flavoquin, Coarsucam
Disease: Malaria
Drug Class: Antimalarials
Date Updated: June 2021
Absorption Model |
First-Order |
Volume of Distribution |
Full PBPK (Method 2) |
Route of Elimination |
CYP2C8 = 72%; Additional HLM = 28% |
Perpetrator DDI |
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Validation |
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Limitations |
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Updates in V19 |
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Simcyp developed Methotrexate compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.
The RES-Pitavastatin file was developed as a CYP2C9, UGT1A3/2B7, OATP1B1/1B3/2B1, NTCP substrate This document provides: 1. Examples of model performance 2. A summary of the key pharmacokinetic features of pitavastatin considered within the model.
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