Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 147 Matches

Ceftazidime_V14R1_AstraZeneca_20200327
Ceftazidime for pediatric predictions.
Avibactam_V15R1_USFDA_20170810
http://onlinelibrary.wiley.com/doi/10.1002/cpt.750/full Avibactam compound file in healthy volunteers. Evaluation of the effect of renal impairment on PK of OAT substrates
EsomeprazoleCapsule_V14R1_AstraZeneca_20200427
https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/cpt.905 Esomeprazole adult compound file for pediatric prediction. The following parameters need to be updated, as compared to Table 2 in the manuscript: Ka=1.331/h, tlag=1h, fu,gut=0.048
Remdesivir&Metabolites_V18R1_Gilead_20210204
Remdesivir (GS-5734) and metabolites adult compound files Adult and pediatric (<40kg and >40kg) workspace files

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