Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 147 Matches

V18 released Simcyp files for antiretroviral drugs
V18 released Simcyp files for antiretroviral drugs
Fluoxetine&Norfluoxetine_V12R2_USFDA_20160511
Optimized, personal communication with Dr. Snoeys
Entecavir_V15R1_USFDA_20170810
Entecavir compound file in healthy volunteers. Evaluation of the effect of renal impairment on PK of OAT substrates. NOTE: file has predicted Vss of 0.98 L/kg. Table 1 value is 0.9 L/kg. http://onlinelibrary.wiley.com/doi/10.1002/cpt.750/full
Maraviroc&Telaprevir&VRT_127394_V15R1_Pfizer_20200405
http://dmd.aspetjournals.org/content/47/5/493.long Maraviroc and Telaprevir/healthy volunteer. The workspace is set up as multiple dose over 10 days to account for the MBI of Telaprevir. The metabolite of Telaprevir (VRT-127394) is included in the workspace.

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