Quickly find freely available drug and population models in our PBPK model repository.
The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.
You can use a suffix operator (*) as the placeholder for end of a term. The query must start with at least one alphanumeric character before the suffix operator. E.g., Rifam* will get you “Rifampicin” and “Rifampin”. For more advanced searching tips click here.
Brand Name(s) include: Fuzeon
Disease: HIV
Drug Class: HIV Entry and Fusion Inhibitor
Date of Review: 2020
Number of Models Reviewed: 1
Number of Models added to the Repository: 1
|
Publication |
Pan, X., Stader, F., Abduljalil, K., Gill, K. L., Johnson, T. N., Gardner, I., & Jamei, M. (2020). Development and Application of a Physiologically-Based Pharmacokinetic Model to Predict the Pharmacokinetics of Therapeutic Proteins from Full-term Neonates to Adolescents. The AAPS journal, 22(4), 76. |
|
Simcyp Version |
V18 |
|
Published Model Application |
Prediction of exposure in noenates |
|
Absorption Model |
First Order |
| Volume of Distribution Details |
Full PBPK |
|
Route of Elimination |
|
|
Perpetrator DDI |
|
|
Advantages and Limitations |
|
|
Model Compound Files |
|
|
2 |