Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 136 Matches

Fexofenadine_RES_V23R1_Simcyp_20230401

Simcyp developed fexofenadine compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Pemigatinib_V19R1_Incyte_20220114

A Pemigatinib PBPK article accepted by CPT PSP with leading author as Tao Ji The submitted workspace files for Pemigatinib is using minimal PBPK model with ADAM functions for Pemigatinib that incorporates CYP3A4-mediated metabolism derived from in vitro data, mass balance data, and clinical PK data, for the purpose of evaluation of clinical DDIs with strong CYP3A inhibitors and/or inducers.

Desloratadine_V14R1_AstraZeneca_20200427
Desloratadine adult compound file for paediatric prediction.
Montelukast_V14R1_AstraZeneca_20200427
Montelukast adult compound file for paediatric prediction.

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