Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

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Found 131 Matches

Fexofenadine_RES_V23R1_Simcyp_20230401

Simcyp developed fexofenadine compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Desloratadine_V14R1_AstraZeneca_20200427
Desloratadine adult compound file for paediatric prediction.
Montelukast_V14R1_AstraZeneca_20200427
Montelukast adult compound file for paediatric prediction.
Tramadol_V14R1_AstraZeneca_20200427
Tramadol adult compound file for pediatric prediction. The following parameters need to be updated, as compared to Table 2 in the manuscript: CYP2D6 0.7, CYP3A4 0.035, CYP2B6 0.1, CLr 6.6 L/hr

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