Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
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Found 126 Matches

Ondansetron_V14R1_AstraZeneca_20200427

Model Files Publication

Ondansetron adult compound file for paediatric prediction.

Search Score: 1

Paclitaxel_RES_V17R1_Simcyp_20180228

Model Files Publication

Simcyp developed Paclitaxel compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Search Score: 1

Probenecid_V12R1_FDA_20150709

Model Files Publication

Supplemental table. Ki against OAT transporters can be changed (sensitivity analysis was conducted in the referenced publication to explore "in vivo" Ki).

Search Score: 1

Chlorzoxazone_RES_V20R1_Simcyp_20210512

Model Files Publication

The RES-Chlorzoxazone file was primarily developed as an inhibitor of CYP3A4. This document provides: 1. Examples of model performance 2. A summary of the key pharmacokinetic features of Chlorzoxazone considered within the model.

Search Score: 1

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Ondansetron_V14R1_AstraZeneca_20200427

Paclitaxel_RES_V17R1_Simcyp_20180228

Probenecid_V12R1_FDA_20150709

Chlorzoxazone_RES_V20R1_Simcyp_20210512

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